

In 2004, Ramesh Babu established a film production company named Krishna Productions Private Ltd in Hyderabad.

In 1997, he was seen in a supporting role in N. The film was directed by Adurthi Saibhaskar and had Rambha acting opposite Ramesh. In 1994, he was seen for the last time in a leading role in the film Pacha Thoranam. In 1993, he once again collaborated with Dasari Narayana Rao for the film Maama Kodalu and was also seen in Anna Chellelu opposite Aamani. In 1991, he was seen in Naa Ille Naa Swargam, also starring his father. In 1989, he was seen in Dasari Narayana Rao's Black Tiger and V.

Bazaar Rowdy became a blockbuster and giving Ramesh his first success as a solo hero. Mugguru Kodukulu also had his father and brother acting alongside him. Kodandarami Reddy's Bazaar Rowdy and in Kaliyuga Karnudu and Mugguru Kodukulu, both directed by his father. In 1988, he was seen in films such as Jandhyala's Chinni Krishnudu, A. The film had Sonam paired alongside Ramesh and Sharada in a vital role. In 1987, he made his comeback as a lead actor with the film Samraat, directed by V. After that, he took a brief hiatus from acting. The film also had his four-year-old brother, Mahesh Babu in a small role. After two years, at the age of 14, he was cast in a vital role in the film Needa, which was directed by Dasari Narayana Rao. In 1977, Ramesh Babu ventured into films as a child actor at the age of 12 with his father's film Manushulu Chesina Dongalu.
